Enzymes of pigmentation (tyrosinase...): understanding and regulation

From our previous results about models for dicopper center – substrate/inhibitor interactions, our present multidisciplinary approach is focused on a deeper understanding at the molecular level of the competitive inhibition mechanism of tyrosinase, the key enzyme involved in melanin (protective pigments) biosynthesis and associated to melanin-disorders.

Collaborations
H. Jamet (SITh, DCM)
R. Hardré / M. Maresca / M. Réglier (ISM2, Univ. Aix-Marseille) 
L. Bubacco (Univ. Padova, Italy)

Supports