HELENE JAMET
Enseignante-Chercheuse
Affiliation
Université Grenoble Alpes
Équipe de recherche
DCM-SITH
Domaines de recherche
chimie quantique, QM/MM, dynamique, docking
Disciplines scientifiques
Chimie théorique, physique, analytique
Habilitation à diriger des recherches
« Modélisation de systèmes biochimiques : exemples et apports méthodologiques »
Buitrago, E., Faure C., Carotti M., Bergantino E., Hardré R., Maresca M., et al.
(2023). Exploiting HOPNO-dicopper center interaction to development of inhibitors for human tyrosinase.
European Journal of Medicinal Chemistry. 248, 115090.
Contaldo, U.., Padrosa D.. R., Jamet H., Albrecht M.., Paradisi F.., & Le Goff A..
(2023). Optimising Electrical Interfacing between the Trimeric Copper Nitrite Reductase and Carbon Nanotubes.
Chem. Eur. J.. 29(47),
Faure, C., d’Hardemare A. du Mouline, Jamet H., Belle C., Bergantino E., Bubacco L., et al.
(2023). Transition State Analogue Molecules as Mechanistic Tools and Inhibitors for Tyrosinase.
Copper Bioinorganic Chemistry. 45-80.
Gillard, M., Piraux G., Daenen M., Abraham M., Troian-Gautier L., Bar L., et al.
(2022). Photo-oxidizing Ruthenium(II) Complexes with Enhanced Visible Light Absorption and G-quadruplex DNA Binding Abilities.
Chemistry – A European Journal. 28,
Buitrago, E., Faure C., Challali L., Bergantino E., Boumendjel A., Bubacco L., et al.
(2021). Ditopic Chelators of Dicopper Centers for Enhanced Tyrosinases Inhibition.
Chemistry – A European Journal. 27, 4384-4393.
Faure, C., Jamet H., Belle C., & Du Moulinet D'Hardemare A.
(2020). Exploring Coumarins Reduction: NaBH4/MeOH versus Nickel Boride Generated In Situ..
ChemistrySelect. 5, 14735-14740.
Lanoe, P-H., Moreno-Betancourt A., Wilson L., Philouze C., Monnereau C., Jamet H., et al.
(2019). Neutral heteroleptic cyclometallated Platinum(II) complexes featuring 2-phenylbenzimidazole ligand as bright emitters in solid state and in solution.
Dyes and Pigments. 162, 967 - 977.
Isaac, J.. A., Mansour A.-T.., David R., Kochem A.., Philouze C., Demeshko S.., et al.
(2018). Tetranuclear and dinuclear phenoxido bridged copper complexes based on unsymmetrical thiosemicarbazone ligands.
Dalt. Trans.. 47, 9665-9676.
Thibon-Pourret, A., Gennarini F., David R., Isaac J. A., Lopez I., Gellon G., et al.
(2018). Effect of Monoelectronic Oxidation of an Unsymmetrical Phenoxido-Hydroxido Bridged Dicopper(II) Complex.
Inorganic Chemistry. 57, 12364-12375.
Gennarini, F., Kochem A., Isaac J., Mansour A-T., Lopez I., Le Mest Y., et al.
(2018). Effect of ligand exchange on the one-electron oxidation process of alkoxo or phenoxo bridged binuclear copper(II) complexes.
Inorganica Chimica Acta. 481, 113 - 119.
Weynand, J., Diman A., Abraham M., Marcelis L., Jamet H., Decottignies A., et al.
(2018). Towards the Development of Photo-Reactive Ruthenium(II) Complexes Targeting Telomeric G-Quadruplex DNA..
Chem. - A Eur. J.. 24, 19216–19227.
Piraux, G., Bar L., Abraham M., Lavergne T., Jamet H., Dejeu J., et al.
(2017). New Ruthenium-Based Probes for Selective G-Quadruplex Targeting..
Chem. - A Eur. J.. 23, 11872–11880.
Gennarini, F., David R., Lopez I., Le Mest Y., Reglier M., Belle C., et al.
(2017). Influence of Asymmetry on the Redox Properties of Phenoxo- and Hydroxo-Bridged Dicopper Complexes: Spectroelectrochemical and Theoretical Studies..
Inorg. Chem.. 56, 7707–7719.
David, R., Jamet H., Niviere V., Moreau Y., & Milet A.
(2017). Iron hydroperoxide intermediate in superoxide reductase: Protonation or dissociation first? MM dynamics and QM/MM metadynamics study..
J. Chem. Theory Comput.. 13, 2987–3004.
Traore, M. D. M., Zwick V., Simoes-Pires C. A., Nurisso A., Issa M., Cuendet M., et al.
(2017). Hydroxyl Ketone-Based Histone Deacetylase Inhibitors To Gain Insight into Class I HDAC Selectivity versus That of HDAC6..
ACS Omega. 2, 1550–1562.
Haudecoeur, R., Carotti M., Gouron A., Maresca M., Buitrago E., Hardre R., et al.
(2017). 2-Hydroxypyridine-N-oxide-Embedded Aurones as Potent Human Tyrosinase Inhibitors..
ACS Med. Chem. Lett.. 8, 55–60.
Buitrago, E., Hardre R., Haudecoeur R., Jamet H., Belle C., Boumendjel A., et al.
(2016). Are Human Tyrosinase and Related Proteins Suitable Targets for Melanoma Therapy?..
Curr. Top. Med. Chem. (Sharjah, United Arab Emirates). 16, 3033–3047.
Isaac, J., Gennarini F., Lopez I., Thibon-Pourret A., David R., Gellon G., et al.
(2016). Room-Temperature Characterization of a Mixed-Valent u-Hydroxodicopper(II,III) Complex..
Inorg. Chem.. 55, 8263–8266.
Lalaoui, N., David R., Jamet H., Holzinger M., Le Goff A., & Cosnier S.
(2016). Hosting Adamantane in the Substrate Pocket of Laccase: Direct Bioelectrocatalytic Reduction of O2 on Functionalized Carbon Nanotubes..
ACS Catal.. 6, 4259–4264.
Lecarme, L., Prado E., De Rache A., Nicolau-Travers M-L., Gellon G., Dejeu J., et al.
(2016). Efficient Inhibition of Telomerase by Nickel-Salophen Complexes..
ChemMedChem. 11, 1133–1136.
Haudecoeur, R., Gouron A., Dubois C., Jamet H., Lightbody M., Hardre R., et al.
(2014). Investigation of Binding-Site Homology between Mushroom and Bacterial Tyrosinases by Using Aurones as Effectors..
ChemBioChem. 15, 1325–1333.
Gouron, A., Milet A., & Jamet H.
(2014). Conformational flexibility of human casein kinase catalytic subunit explored by metadynamics..
Biophys. J.. 106, 1134–1141.
Buitrago, E., Vuillamy A., Boumendjel A., Yi W., Gellon G., Hardre R., et al.
(2014). Exploring the Interaction of N/S Compounds with a Dicopper Center: Tyrosinase Inhibition and Model Studies..
Inorg. Chem.. 53, 12848–12858.
Bochot, C., Gouron A., Bubacco L., Milet A., Philouze C., Reglier M., et al.
(2014). Probing kojic acid binding to tyrosinase enzyme: insights from a model complex and QM/MM calculations..
Chem. Commun. (Cambridge, United Kingdom). 50, 308–310.
Lecarme, L., Prado E., De Rache A., Nicolau-Travers M-L., Bonnet R., Van der Heyden A., et al.
(2014). Interaction of Polycationic Ni(II)-Salophen Complexes with G-Quadruplex DNA..
Inorg. Chem.. 53, 12519–12531.
Milet, A., Gouron A., David R., Jamet H., & Vallee Y..
(2013). En route to life: The very first step..
Abstracts of Papers, 246th ACS National Meeting {&} Exposition, Indianapolis, IN, United States, September 8-12, 2013.
Papadakis, R., Rivière E., Giorgi M., Jamet H., Rousselot-Pailley P., Reglier M., et al.
(2013). Structural and Magnetic Characterization of a Tetranuclear Copper(II) Cubane Stabilized by Intramolecular Metal Cation-$π$ Interactions..
Inorg. Chem.. 52, 5824–5830.
Bochot, C., Favre E., Dubois C., Baptiste B., Bubacco L., Carrupt P-A., et al.
(2013). Unsymmetrical Binding Modes of the HOPNO Inhibitor of Tyrosinase: From Model Complexes to the Enzyme..
Chem. - A Eur. J.. 19, 3655–3664.
Reddy, P. Venkatram, Smith J., Kamath A., Jamet H., Veyron A., Koos P., et al.
(2013). Asymmetric Approach to Hyacinthacines B1 and B2..
J. Org. Chem.. 78, 4840–4849.
Dubois, C., Haudecoeur R., Orio M., Belle C., Bochot C., Boumendjel A., et al.
(2012). Versatile Effects of Aurone Structure on Mushroom Tyrosinase Activity..
ChemBioChem. 13, 559–565.
Nasiri, R., Zahedi M., Jamet H., & Moosavi-Movahedi A. Akbar.
(2012). Theoretical studies on models of lysine-arginine cross-links derived from $\alpha$-oxoaldehydes: a new mechanism for glucosepane formation..
J. Mol. Model.. 18, 1645–1659.
Kochem, A., Orio M., Philouze C., Jamet H., Du Moulinet D'Hardemare A., & Thomas F.
(2011). Radicals of Free and Zinc(II)-Coordinated $\alpha$-Azophenols..
Eur. J. Inorg. Chem.. 45–48.
Retegan, M., Jamet H., Maji P., Gimbert Y., Oltean M., & Milet A.
(2011). MESP: An efficient method to validate an ONIOM partition for the modelization of phosphine ligands commonly used in the Pauson-Khand reaction..
Comput. Theor. Chem.. 965, 231–235.
Durot, S., Hossain L. H., Hamman S., Jamet H., Orio M., Gautier-Luneau I., et al.
(2010). Separation of Geometric Isomers of a Dicopper Complex by Using a 19F-Labeled Ligand: Dynamics, Structures, and DFT Calculations..
Inorg. Chem.. 49, 7832–7840.
Retegan, M., Milet A., & Jamet H.
(2010). Comparative Theoretical Studies of the Phosphomonoester Hydrolysis Mechanism by Purple Acid Phosphatases..
J. Phys. Chem. A. 114, 7110–7116.
Torelli, S., Orio M., Pécaut J., Jamet H., Le Pape L., & Menage S..
(2010). A \Cu2S\}2+ Mixed-Valent Core Featuring a Cu-Cu Bond.}.
Angew. Chemie, Int. Ed.. 49, 8249–8252, S8249/1–S8249/10.
Gautier-Luneau, I., Suffren Y., Jamet H., & Pilme J..
(2010). Reinterpretation of three crystal structures of alkali oxoiodate(V). Description of the [I3O8]- anion and the infinite 2D [I3O8-]∞ anion..
Zeitschrift fuer Anorg. und Allg. Chemie. 636, 1368–1379.
Retegan, M., Milet A., & Jamet H.
(2009). Exploring the Binding of Inhibitors Derived from Tetrabromobenzimidazole to the CK2 Protein Using a QM/MM-PB/SA Approach..
J. Chem. Inf. Model.. 49, 963–971.
Rammal, W., Jamet H., Philouze C., Pierre J-L., Saint-Aman E., & Belle C.
(2009). Structural and redox properties in thioether-based (N/S) copper(II/I) complexes: Experimental and theoretical investigations..
Inorganica Chim. Acta. 362, 2321–2326.
Jamet, H., Jourdan M., & Dumy P.
(2008). NMR and Theoretical Calculations: A Unified View of the Cis/Trans Isomerization of 2-Substituted Thiazolidine Containing Peptides..
J. Phys. Chem. B. 112, 9975–9981.
Jamet, H., & Borshch S. A.
(2004). Comparison of polyoxo and polyoxothiometallate rings: a theoretical approach..
New J. Chem.. 28, 490–494.
Thomas, F., Jarjayes O., Jamet H., Hamman S., Saint-Aman E., Duboc C., et al.
(2004). How single and bifurcated hydrogen bonds influence proton-migration rate constants, redox, and electronic properties of phenoxyl radicals..
Angew. Chemie, Int. Ed.. 43, 594–597.
Diplômes :
1993 : Admission ENS Lyon ; 1996 : Agrégation de Sciences Physiques (option Chimie) ;
2000 :Thèse ENS Lyon :« Études théoriques de la structure électronique de polyoxométallates » sous la direction du Dr. S. Borshch ; 2012 : Habilitation à diriger des Recherches, spécialité CHIMIE :« Modélisation de systèmes biochimiques : exemples et apports méthodologiques ». Université de Grenoble.
Carrières :
1997-2000 :Ens Lyon Agrégée préparatrice, 2000-2002 :Post-doctorat: boursière Fondation Humboldt dans le groupe du Prof. Sauer à la Humboldt Universitat Berlin
Depuis Sept. 2002 : Maître de Conférences section CNU 31 université Grenoble Alpes
Responsabilités :
2008-2011- Membre conseil unité DCM, 2008-2018 : Membre commission séminaire du DCM, Depuis 2016 :Membre du comité scientifique du Labex Arcane.
2003-2007 : responsable de l’UE « Structure de la Matière » niveau L1, Depuis 2007 : responsable de l’UE « Liaison Chimique» niveau L3 Chimie-Biologie, Depuis 2015 : responsable du M1 Chemistry UGA.
1993 : Admission ENS Lyon ; 1996 : Agrégation de Sciences Physiques (option Chimie) ;
2000 :Thèse ENS Lyon :« Études théoriques de la structure électronique de polyoxométallates » sous la direction du Dr. S. Borshch ; 2012 : Habilitation à diriger des Recherches, spécialité CHIMIE :« Modélisation de systèmes biochimiques : exemples et apports méthodologiques ». Université de Grenoble.
Carrières :
1997-2000 :Ens Lyon Agrégée préparatrice, 2000-2002 :Post-doctorat: boursière Fondation Humboldt dans le groupe du Prof. Sauer à la Humboldt Universitat Berlin
Depuis Sept. 2002 : Maître de Conférences section CNU 31 université Grenoble Alpes
Responsabilités :
2008-2011- Membre conseil unité DCM, 2008-2018 : Membre commission séminaire du DCM, Depuis 2016 :Membre du comité scientifique du Labex Arcane.
2003-2007 : responsable de l’UE « Structure de la Matière » niveau L1, Depuis 2007 : responsable de l’UE « Liaison Chimique» niveau L3 Chimie-Biologie, Depuis 2015 : responsable du M1 Chemistry UGA.
