Voltammetric detection of heparin based on anion exchange at electropolymeric film of pyrrole-alkylammonium cationic surfactant and MWCNTs composite.
Electropolymeric film of pyrrole-alkylammonium (A2) cationic surfactant and multi-wall C nanotubes (MWCNTs) composite was firstly used to absorb Fe(CN)63-/4- ions as electrochem. markers to develop amperometric assay for electrochem. inactive heparin. The electrochem. behaviors of the modified Pt electrodes were characterized by cyclic voltammetry and electrochem. impedance spectroscopy. A quite stable and well-defined redox peaks of the confined Fe(CN)63-/4- with neg. shifted potentials compared to the Fe(CN)63-/4$\backslash$- in aq. soln. were obsd. at Fe(CN)63-/4-/polyA2-MWCNTs/Pt. Importantly, the ion exchange of the small anions, Fe(CN)63-/4- by polyanions, heparin at polyA2-MWCNTs films was obsd. Thereafter, an amperometric assay for heparin based on anion exchange at Fe(CN)63-/4-/polyA2-MWCNTs/Pt was developed. The linear range to detect heparin with differential pulse voltammetry (DPV) is 0.1-8.0 $μ$M with the limit of detection of 0.1 $μ$M. [on SciFinder(R)]
Références
- Titre
- Voltammetric detection of heparin based on anion exchange at electropolymeric film of pyrrole-alkylammonium cationic surfactant and MWCNTs composite.
- Type de publication
- Article de revue
- Année de publication
- 2013
- Auteurs
- Ding, Shou-Nian, Chen Jian-Fei, Xia Jiangyan, Wang Yi-Hong, and Cosnier Serge
- Revue
- Electrochem. commun.
- Volume
- 34
- Pagination
- 339–343
- ISSN
- 1388-2481
Soumis le 12 avril 2018