Total Synthesis of Marine Sponge Bis(indole) Alkaloids of the Topsentin Class.
{The synthesis of four natural bis(indole) alkaloids of the topsentin class is described. Their bis(indole) $\alpha$-carbonylimidazoline and subsequently bis(indole) $\alpha$-carbonylimidazole moieties have been built via the condensation between indolic $\alpha$-ketothioimidate salts and 1-(indol-3'-yl)-1,2-diaminoethane. This is the first total synthesis of compds. isobromodeoxytopsentin I (double bond
Références
- Titre
- Total Synthesis of Marine Sponge Bis(indole) Alkaloids of the Topsentin Class.
- Type de publication
- Article de revue
- Année de publication
- 2007
- Auteurs
- Guinchard, Xavier, Vallee Yannick., and Denis Jean-Noël
- Revue
- J. Org. Chem.
- Volume
- 72
- Pagination
- 3972–3975
- ISSN
- 0022-3263
Soumis le 12 avril 2018