Total synthesis of (+)-Hyacinthacine A6 and (+)-Hyacinthacine A7.
(+)-Hyacinthacines A6 and A7 were synthesized from a common, late-stage intermediate, prepd. in high yield through stereoselective [2+2] cycloaddn. of dichloroketene to a chiral enol ether. The flexibility of aminonitrile chem. is central to the approach.
Références
- Titre
- Total synthesis of (+)-Hyacinthacine A6 and (+)-Hyacinthacine A7.
- Type de publication
- Article de revue
- Année de publication
- 2014
- Auteurs
- Smith, Julien, Kamath Anushree, Greene Andrew E., and Delair Philippe.
- Revue
- Synlett
- Volume
- 25
- Pagination
- 209–212
- ISSN
- 0936-5214
Soumis le 12 avril 2018