Total Syntheses of Brominated Marine Sponge Alkaloids.
Total syntheses of six brominated marine sponge bis(indole) alkaloids of the hamacanthin, spongotine, and topsentin classes are described. Retrosynthetic anal. shows that their structures all include the 1-(6'-bromoindol-3'-yl)-1,2-diaminoethane unit I. This key moiety has been prepd. from a brominated indolic N-hydroxylamine via synthetic intermediate II. [on SciFinder(R)]
Références
- Titre
- Total Syntheses of Brominated Marine Sponge Alkaloids.
- Type de publication
- Article de revue
- Année de publication
- 2007
- Auteurs
- Guinchard, Xavier, Vallee Yannick., and Denis Jean-Noël
- Revue
- Org. Lett.
- Volume
- 9
- Pagination
- 3761–3764
- ISSN
- 1523-7060
Soumis le 12 avril 2018