Tandem catalytic C(sp3)-H amination/sila-Sonogashira-Hagihara coupling reactions with iodine reagents

A new tandem C-N and C-C bond-forming reaction has been achieved through Rh(II) /Pd(0) catalysis. The sequence first involves an iodine(III) oxidant, then the in situ generated iodine(I) by-product is used as a coupling partner. The overall process demonstrates the synthetic value of iodoarenes produced in trivalent iodine reagent mediated oxidations.

Références

Titre
Tandem catalytic C(sp3)-H amination/sila-Sonogashira-Hagihara coupling reactions with iodine reagents
Type de publication
Article de revue
Année de publication
2015
Revue
Angewandte Chemie - International Edition
Volume
54
Pagination
5697–5701
ISSN
15213773
ISBN
1521-3773
Soumis le 25 septembre 2018