Synthetic approaches for iron type chelators.

A review. Synthetic iron chelators (siderophores mimics) are of paramount interest as clin. iron removal agents (iron overload is one of the most common poisoning) and water-sol. iron complexes can be used to alleviate iron deficiency in plants. Moreover, some addnl. properties may be needed for a precise function (as examples, probes for studying metal transport, diagnostic tools, agent suited for vectorisation...). The authors described in this review the org. syntheses of selected typical examples from the authors' works such as: (a) amphiphilic chelators based on catechol groups; (b) mixed ligands based on catechol and quinoline groups; (c) quinolobactin, a natural siderophore; and (d) oxinobactin, a biomimetic synthetic analog of enterobactin involving 8-hydroxyquinoline chelating subunits. [on SciFinder(R)]

Références

Titre
Synthetic approaches for iron type chelators.
Type de publication
Article de revue
Année de publication
2010
Revue
Mini. Rev. Org. Chem.
Volume
7
Pagination
125–133
ISSN
1570-193X
Soumis le 12 avril 2018