SmI2-mediated reductive cross-coupling reactions of $\alpha$-cyclopropyl nitrones.
Three new $\alpha$-cyclopropyl nitrones have been synthesized as mechanistic probes for reductive cross-coupling reactions of nitrones. The $\alpha$-cyclopropylcarbinyl radical intermediate formed by single electron transfer from SmI2 to these nitrones is not prone to ring opening, due to a unique stabilization by the vicinal N-O-Sm system. Consequently, $\beta$-cyclopropyl hydroxylamines could be prepd. in high yield from $\alpha$-cyclopropyl nitrones. [on SciFinder(R)]
Références
- Titre
- SmI2-mediated reductive cross-coupling reactions of $\alpha$-cyclopropyl nitrones.
- Type de publication
- Article de revue
- Année de publication
- 2010
- Auteurs
- Burchak, Olga N., Masson Geraldine, and Py Sandrine
- Revue
- Synlett
- Pagination
- 1623–1626
- ISSN
- 0936-5214
Soumis le 12 avril 2018