RGD-cyclam conjugate: Synthesis and potential application for positron emission tomography.

Cyclam and DOTA-contg. positron emission tomog. radiotracers were prepd. by using a modular chem. strategy based on peptide synthesis and chemoselective ligations. These mols. encompass two functional domains, one a tumor "homing" domain and the other a chelating ligand for copper allowing nuclear imaging of tumors. [on SciFinder(R)]

Références

Titre
RGD-cyclam conjugate: Synthesis and potential application for positron emission tomography.
Type de publication
Article de revue
Année de publication
2010
Revue
Bioorg. Med. Chem. Lett.
Volume
20
Pagination
5422–5425
ISSN
0960-894X
Soumis le 12 avril 2018