Redox-Active Biomolecular Architectures and Self-Assembled Monolayers Based on a Cyclodecapeptide Regioselectively Addressable Functional Template.

A nanometer scale redox active biomol. architecture has been successfully synthesized through an efficient chemoselective oxime based coupling between ferrocenyl groups and a regioselectively addressable cyclodecapeptide. This mol. tool exhibits electronic, structural, and chem. properties driven by the biomimetic recognition activity of the polypeptide skeleton assocd. to the well-defined electrochem. activity of metallocenyl probes. Biomol. materials obtained by confinement of the redox cyclopeptide in self-assembled monolayers on gold surfaces shows efficient through-bond electron transfer from the ferrocenes to the electrode surface via the peptidic backbone, as well as markedly improved sensing properties toward anionic species in org. electrolyte, as compared to those obsd. in homogeneous soln. [on SciFinder(R)]

Références

Titre
Redox-Active Biomolecular Architectures and Self-Assembled Monolayers Based on a Cyclodecapeptide Regioselectively Addressable Functional Template.
Type de publication
Article de revue
Année de publication
2006
Revue
Langmuir
Volume
22
Pagination
8134–8143
ISSN
0743-7463
Soumis le 12 avril 2018