Pyrrolic derivatives, processes for preparing the same and their uses as a antibacterial drug.
The invention relates to pyrrolic derivs. of formula I, processes for their prepn., and their use as antibacterial drugs. Compds. of formula I wherein R1 - R6 are independently H, (un)branched C1-7 alkyl, (un)branched C2-7 alkenyl, (un)branched C2-7 alkynyl, C3-7 cycloalkyl, etc.; R is H, CHO, acyl, CO2H and derivs., (un)branched C1-7 alkyl, etc.; and pharmaceutically acceptable salts thereof, are claimed. Example compd. II was prepd. by arylation of N-propylidene-benzylamine N-oxide with 3-acetyl-2,4-dimethylpyrrole. The invention compds. were evaluated for their antibacterial activity (data given).
Références
- Titre
- Pyrrolic derivatives, processes for preparing the same and their uses as a antibacterial drug.
- Type de publication
- Brevet
- Année de publication
- 2013
- Patent Number
- WO 2013117749 A1
Soumis le 15 mai 2018