Département de chimie moléculaire

The design of nanostructured biol. architectures based on host-guest interactions between $\beta$-cyclodextrin and adamantane was investigated on SWCNT coatings using glucose oxidase (GOX) as biomol. model. $\beta$-Cyclodextrin tagged GOX was immobilized on adamantane functionalized carbon nanotubes, deposited on platinum electrodes. Different functionalization techniques to attach "pyrene adamantane" on nanotubes were studied and compared in terms of the performances of the subsequently constructed glucose biosensors. The best results were obtained by dipping the nanotube deposit into a pyrene-adamantane soln. followed by electropolymn. of the adsorbed pyrene monolayer. The constructed biosensor exhibited a good linear response toward glucose concns. between 2×10-7 M and 1.6×10-3 M. The max. c.d. and glucose sensitivity were 154.9 $μ$A cm-2 and 14.4 mA M-1 cm-2, resp. [on SciFinder(R)]