Preparation of functionalized hydrogels and their applications as biosensors, pharmaceutical carriers, and bioreactors.

Functionalized hydrogels comprise a hydrogel backbone selected from carrageenan, chitosan, hyaluronic acid, cellulose, and alginate polymer and at least one polymerizable moiety selected from thiophene, aniline, and pyrrole. Hydrogels functionalized with a polymerizable moiety in the form of films and gels can be used as biosensors, pharmaceutical carriers, and bioreactors with a second element selected from cells, proteins, DNA, or other mols. Thus, N-(3-aminopropyl)pyrrole was reacted with sodium alginate (Protanal LF 10/60) in the presence of N-hydroxysulfosuccinimide and 1-ethyl-3-dimethylaminopropyl-3-ethylcarbodiimide to receive the pyrrole modified alginate. [on SciFinder(R)]

Références

Titre
Preparation of functionalized hydrogels and their applications as biosensors, pharmaceutical carriers, and bioreactors.
Type de publication
Brevet
Année de publication
2007
Patent Number
WO 2007038982 A1
Soumis le 23 mai 2018