Organocatalyst-mediated enantioselective intramolecular Michael addition of aldehydes to vinyl sulfones
Chiral amines with a hydrogen bond donor promote the intramolecular conjugate addition of aldehydes to vinyl sulfones. Chiral cyclic sulfone-aldehydes are obtained in good yields with an ee of up to 82%.
Références
- Titre
- Organocatalyst-mediated enantioselective intramolecular Michael addition of aldehydes to vinyl sulfones
- Type de publication
- Article de revue
- Année de publication
- 2010
- Auteurs
- Bournaud, Chloée, Marchal Estelle, Quintard Adrien, Sulzer-Mossé Sarah, and Alexakis Alexandre
- Revue
- Tetrahedron: Asymmetry
- Volume
- 21
- Ticket
- 13
- Pagination
- 1666–1673
- ISSN
- 0957-4166
Soumis le 7 septembre 2022