One-pot approach to well-defined biomolecular assemblies by orthogonal chemoselective ligations.

Well-defined biomol. assemblies are synthesized using orthogonal oxime bond formation and copper(I)-mediated alkyne-azide cycloaddn. reactions in a stepwise or in a one-pot approach. To illustrate this strategy, regioselective ligation of biol. relevant peptides onto a cyclopeptidic scaffold was performed. [on SciFinder(R)]

Références

Titre
One-pot approach to well-defined biomolecular assemblies by orthogonal chemoselective ligations.
Type de publication
Article de revue
Année de publication
2009
Revue
Angew. Chemie, Int. Ed.
Volume
48
Pagination
2576–2579
ISSN
1433-7851
Soumis le 12 avril 2018