Non-invasive tools for detecting vulnerable atherosclerotic plaques.

The present invention relates to a polypeptide comprising or constituted of the sequence RILAR (SEQ ID NO: 3), the use thereof in imaging methods, in diagnostic or prognostic methods and for use as a medicament. Mice with focal atherosclerotic lesions were injected with 99mTc-labeled HGRANLRILARY and subjected to SPECT imaging. There was higher tracer activity in the atherosclerotic lesion than in the contralateral vessel, resulting in a significantly higher mean tracer activity. [on SciFinder(R)]

Références

Titre
Non-invasive tools for detecting vulnerable atherosclerotic plaques.
Type de publication
Brevet
Année de publication
2010
Patent Number
WO 2010079156 A1
Soumis le 23 mai 2018