Département de chimie moléculaire

New types of glycopolymers have been designed and evaluated as multivalent systems for lectin recognition. They were prepd. by living Anionic Ring-Opening Polymn. (AROP) of disubstituted cyclopropane-1,1-dicarboxylates and thiol-ene post-modification. Fully modified oligomers with single or geminal sugar substituents located on every third carbon alongside the macromol. scaffold were obtained under mild conditions. The resulting glycopolymers have shown efficient binding potency towards Con A. [on SciFinder(R)]