Département de chimie moléculaire

3D scaffolds with different pore sizes, using single-walled carbon nanotubes (SWCNTs) and nanoparticles of different size were constructed. Biotinylated glucose oxidase (GOX-B) and anti-cholera toxin (anti-CT) were immobilized onto the one and 2 level nanoscaffolds, functionalized with pyrene-$\beta$-cyclodextrin for the construction of glucose based enzyme sensors and immunosensors, resp. For enzyme sensors, highest c.d. and sensitivity (41.72 $μ$A cm-2, 3 mA M-1 cm-2) were obtained with 2 level scaffolds made with 100 nm nanoparticles. In contrast to this, for immunosensors, highest c.d. and sensitivity (11.71 $μ$A cm-2, 116.2 $μ$A -1 cm-2) were obtained with 2 level scaffolds made with 500 nm nanoparticles, indicating that the pore sizes can be adjusted using different size of nanoparticles for the resp. applications. [on SciFinder(R)]