Nanotubes and nanoparticles based 3D scaffolds for the construction of high performance biosensors.

3D scaffolds with different pore sizes, using single-walled carbon nanotubes (SWCNTs) and nanoparticles of different size were constructed. Biotinylated glucose oxidase (GOX-B) and anti-cholera toxin (anti-CT) were immobilized onto the one and 2 level nanoscaffolds, functionalized with pyrene-$\beta$-cyclodextrin for the construction of glucose based enzyme sensors and immunosensors, resp. For enzyme sensors, highest c.d. and sensitivity (41.72 $μ$A cm-2, 3 mA M-1 cm-2) were obtained with 2 level scaffolds made with 100 nm nanoparticles. In contrast to this, for immunosensors, highest c.d. and sensitivity (11.71 $μ$A cm-2, 116.2 $μ$A -1 cm-2) were obtained with 2 level scaffolds made with 500 nm nanoparticles, indicating that the pore sizes can be adjusted using different size of nanoparticles for the resp. applications. [on SciFinder(R)]

Références

Titre
Nanotubes and nanoparticles based 3D scaffolds for the construction of high performance biosensors.
Type de publication
Article de revue
Année de publication
2014
Revue
MRS Online Proc. Libr.
Volume
1700
Pagination
535/1–535/6, 6 pp.
ISSN
1946-4274
Soumis le 12 avril 2018