Département de chimie moléculaire

Multivalent mannosides with inherent macrophage recognition abilities{,} built on β-cyclodextrin{,} RAFT cyclopeptide or peptide dendrimer cores{,} trigger selective inhibition of lysosomal β-glucocerebrosidase or α-mannosidase depending on valency and topology{,} offering new opportunities in multitargeted drug design.