MiPNO, a new chiral cyclic nitrone for enantioselective amino acid synthesis: the cycloaddition approach.
The resoln. of chiral nitrones via derivatization of hydroxylamines was applied to MiPNO, a new, stable, easily prepd. chiral cyclic nitrone. The application of MiPNO in totally regio- and diastereo-selective 1,3-dipolar cycloaddn. reactions provides an expeditious enantioselective access to unusual $\gamma$-hydroxy $\alpha$-amino acids. [on SciFinder(R)]
Références
- Titre
- MiPNO, a new chiral cyclic nitrone for enantioselective amino acid synthesis: the cycloaddition approach.
- Type de publication
- Article de revue
- Année de publication
- 2010
- Auteurs
- Thiverny, Maryse, Philouze Christian, Chavant Pierre-Yves, and Blandin Véronique
- Revue
- Org. Biomol. Chem.
- Volume
- 8
- Pagination
- 864–872
- ISSN
- 1477-0520
- Mots-clés
- aminoamide condensation methyl butanone oxidn resoln acylation cyclic nitrone MiPNO enantioselective synthesis cycloaddn MiPNO chiral cyclic nitrone hydroxy amino acid enantioselective synthesis
- DOI
- 10.1039/B918612C
Soumis le 12 avril 2018