Kinetic Resolution in the [2+2] Cycloaddition of Ketenes: An Experimental and Theoretical Study.

The kinetic resoln. of Z and E olefins by [2+2] cycloaddn. with ketenes allows the isolation of pure E olefin, as well as the synthesis of pure cis-cyclobutanones, starting from Z/E mixts. A computational rationale for this kinetic difference is reported. The obtained difference of energy of activation matches with the exptl. results.

Références

Titre
Kinetic Resolution in the [2+2] Cycloaddition of Ketenes: An Experimental and Theoretical Study.
Type de publication
Article de revue
Année de publication
2015
Revue
Chem. Eur. J.
Volume
21
Pagination
3876–3881
ISSN
0947-6539
Soumis le 12 avril 2018