An Iron/Amine-Catalyzed Cascade Process for the Enantioselective Functionalization of Allylic Alcohols

Three is a lucky number: An enantioselective transformation of allylic alcohols into beta-chiral saturated alcohols has been developed by combining two distinct metal- and organocatalyzed catalytic cycles. This waste-free triple cascade process merges an iron-catalyzed borrowing-hydrogen step with an aminocatalyzed nucleophilic addition reaction.

Références

Titre
An Iron/Amine-Catalyzed Cascade Process for the Enantioselective Functionalization of Allylic Alcohols
Type de publication
Article de revue
Année de publication
2013
Revue
Angewandte Chemie International Edition
Volume
52
Ticket
49
Pagination
12883–12887
Soumis le 7 septembre 2022