Integrin and matrix metalloprotease dual-targeting with an MMP substrate-RGD conjugate.
A fluorescent clustered RGD-contg. ligand encompassing an MMP substrate was designed and successfully used in vivo for the dual-targeting of $\alpha$V$\beta$3 integrin receptors and MMP-9 extracellular proteases in the tumor region. [on SciFinder(R)]
Références
- Titre
- Integrin and matrix metalloprotease dual-targeting with an MMP substrate-RGD conjugate.
- Type de publication
- Article de revue
- Année de publication
- 2013
- Auteurs
- Wenk, Christiane H. F., Josserand Veronique, Dumy Pascal, Coll Jean-Luc, and Boturyn Didier
- Revue
- Org. Biomol. Chem.
- Volume
- 11
- Pagination
- 448–452
- ISSN
- 1477-0520
Soumis le 12 avril 2018