Integrin and matrix metalloprotease dual-targeting with an MMP substrate-RGD conjugate.

A fluorescent clustered RGD-contg. ligand encompassing an MMP substrate was designed and successfully used in vivo for the dual-targeting of $\alpha$V$\beta$3 integrin receptors and MMP-9 extracellular proteases in the tumor region. [on SciFinder(R)]

Références

Titre
Integrin and matrix metalloprotease dual-targeting with an MMP substrate-RGD conjugate.
Type de publication
Article de revue
Année de publication
2013
Revue
Org. Biomol. Chem.
Volume
11
Pagination
448–452
ISSN
1477-0520
Soumis le 12 avril 2018