Improved preparation of 4,6,6-trimethyl-1,3,2-dioxaborinane and its use in a simple [PdCl2(TPP)2]-catalyzed borylation of aryl bromides and iodides.
A convenient prepn. of 4,6,6-trimethyl-1,3,2-dioxaborinane (MethylPentaneDiolBorane, MPBH) and its use in the [PdCl2(PPh3)2]-catalyzed borylation of aryl bromides and iodides is reported. The boronic esters undergo rapid Suzuki coupling reactions in the presence of cesium fluoride. Thus, MPBH is an excellent alternative to pinacolborane for Pd-catalyzed borylation and cross-coupling reactions. [on SciFinder(R)]
Références
- Titre
- Improved preparation of 4,6,6-trimethyl-1,3,2-dioxaborinane and its use in a simple [PdCl2(TPP)2]-catalyzed borylation of aryl bromides and iodides.
- Type de publication
- Article de revue
- Année de publication
- 2008
- Auteurs
- PraveenGanesh, Nageswaran, and Chavant Pierre-Yves
- Revue
- European J. Org. Chem.
- Pagination
- 4690–4696
- ISSN
- 1434-193X
Soumis le 12 avril 2018