Highly Diastereoselective and Irreversible Aldol Reactions of N-Sulfonylimidates.

A mild method for the aldolization of N-sulfonylimidates was developed. The reaction proceeded in excellent diastereoselectivity to provide a range of useful beta-hydroxyimidates in high yield. The innate reversibility of the reaction was suppressed by the use of a titanium complex as a Lewis acid.

Références

Titre
Highly Diastereoselective and Irreversible Aldol Reactions of N-Sulfonylimidates.
Type de publication
Article de revue
Année de publication
2016
Revue
Synthesis
Volume
48
Pagination
3413–3419
ISSN
1437-210X
Soumis le 12 avril 2018