Heterolignans: Stereoselective synthesis of an 11-amino analog of azaelliptitoxin.
The 11-amino-azaelliptitoxin analog (11R,11aS,5R)-I has been prepd. stereoselectively in eight steps and 24{%} overall yield from com. available (S)-glycidol via the original enantiopure chiral $\alpha$-amino aldehyde II, used as chiral precursor for the creation of the two other stereogenic centers of the target framework. [on SciFinder(R)]
Références
- Titre
- Heterolignans: Stereoselective synthesis of an 11-amino analog of azaelliptitoxin.
- Type de publication
- Article de revue
- Année de publication
- 2008
- Auteurs
- Routier, Julie, Calancea Mihaela, David Marion, Vallee Yannick., and Denis Jean-Noël
- Revue
- European J. Org. Chem.
- Pagination
- 5687–5691
- ISSN
- 1434-193X
Soumis le 12 avril 2018