Département de chimie moléculaire

A new type of amperometric glucose biosensor based on alginate (Alg)/layered double hydroxides (LDHs) org.-inorg. composite film is described. This hybrid material combines the advantages of an org. biopolymer, Alg and inorg. LDHs. Glucose oxidase (GOD) immobilized in the material maintained its activity. The composite films were characterized by UV-visible. GOD retained the essential feature of its native structure in the composite film. The Alg/LDHs/GOD-modified platinum electrode exhibited a fast response to glucose (achieve 95{%} of the max. in 10 s), which provided a linear response to glucose over a concn. range of 1.6 × 10-5 - 2 × 10-3 M with a detection limit of 4 × 10-5 M based on S/N = 3. Furthermore, the biosensor exhibited excellent long-term stability, and satisfactory reproducibility. It retained 87{%} of its original activity after being used for 28 days. [on SciFinder(R)]