Ferrocyanide-Ferricyanide Redox Couple Induced Electrochemiluminescence Amplification of Carbon Dots for Ultrasensitive Sensing of Glutathione.

Here the authors report a novel solid-state ECL sensor for ultrasensitive sensing of glutathione (GSH) based on ferrocyanide-ferricyanide redox couple (Fe(CN)63-/4-) induced electrochemiluminescence (ECL) amplification of carbon dots (C-dots). The electropolymn. of C-dots and (11-pyrrolyl-1-yl-undecyl) triethylammonium tetrafluoroborate (A2) enabled immobilization of the hydrophilic C-dots on the surface of glassy carbon electrode (GCE) perfectly, while the excellent cond. of polypyrrole was exploited to accelerate electron transfer between them. The Fe(CN)63-/4- can expeditiously convert the C-dots and S2O82- to C-dot.bul.- and SO4.bul.-, resp. High yields of the excited state C-dots (C-dots*) were obtained, and a ∼ 10-fold ECL amplification was realized. The C-dots* obtained through the recombination of electron-injected and hole-injected processes may be impeded due to the interference of GSH to K2S2O8. Therefore, the constructed sensor for GSH showed a detection limit down to 54.3 nM (S/N = 3) and a wide linear range from 0.1-1.0 $μ$M with a correlation coeff. of 0.997. [on SciFinder(R)]

Références

Titre
Ferrocyanide-Ferricyanide Redox Couple Induced Electrochemiluminescence Amplification of Carbon Dots for Ultrasensitive Sensing of Glutathione.
Type de publication
Article de revue
Année de publication
2015
Revue
Anal. Chem. (Washington, DC, United States)
Volume
87
Pagination
11150–11156
ISSN
0003-2700
Soumis le 12 avril 2018