Expanding the scope of oxime ligation: facile synthesis of large cyclopeptide-based glycodendrimers.

A new series of 64-valent glycodendrimers was prepd. in excellent yield and purity using a divergent and iterative strategy based on oxime ligation. Enzyme-linked lectin assays revealed the first nanomolar inhibitor for the fucose-specific lectin isolated from Ulex europaeus. [on SciFinder(R)]

Références

Titre
Expanding the scope of oxime ligation: facile synthesis of large cyclopeptide-based glycodendrimers.
Type de publication
Article de revue
Année de publication
2013
Revue
Chem. Commun. (Cambridge, United Kingdom)
Volume
49
Pagination
10796–10798
ISSN
1359-7345
Soumis le 12 avril 2018