Département de chimie moléculaire

The authors describe herein the synthesis and electrochem. polymn. of a viologen monomer functionalized by a biotin group and the use of its redox properties for the impedimetric sensing of protein binding. The electrochem. oxidn. of the pyrrole group at 0.85 V in CH3CN led to a biotinylated polypyrrole film allowing the successive anchoring of an avidin layer and a biotinylated cholera toxin layer. EIS performed at -0.45 V/SCE without redox probe in soln. showed the specific immobilization of the anti-cholera toxin antibody. [on SciFinder(R)]