Département de chimie moléculaire

Single-walled carbon nanotubes (SWCNTs) are considered nowadays as promising alternatives for sensor and biosensor development. The anal. capabilities of this material as sensor material are reported. Biotin functionalized and pristine SWCNTs were deposited onto electrodes out of dispersions with different concns. The amt. of deposited SWCNTs can be controlled by the detn. of capacitive charges of the layers. The electrochem. behavior of SWCNTs coatings was investigated by cyclic voltammetry with potassium hexacyanoferrate as redox probe. Their electro-catalytic effect towards the electrochem. H2O2 redn. was evaluated. The strong $π$ interactions between pyrene and SWCNTs have been exploited for the non-covalent attachment of a pyrene-biotin deriv. on the pristine nanotube surface. The latter allowed the immobilization of biotinylated glucose oxidase via an avidin bridge by affinity interactions. The amperometric response of the biosensor to glucose was recorded at 0.7 V vs. a SCE. The glucose sensitivity and max. c.d. were 560 $μ$AM-1cm-2 and 14 $μ$A/cm2, resp. [on SciFinder(R)]