An efficient method for the synthesis of unsymmetrical 2,2'-bis(pyrrolyl)alkanes.
A new strategy for the prepn. of unsym. 2,2'-bis(pyrrolyl)alkanes has been developed. It involved the condensation of pyrrole derivs. onto N-benzylhydroxylamines in the presence of HCl. This two-step procedure provided access to a wide variety of 2,2'-dipyrromethanes, e.g. I. It has also been extended to the synthesis of tripyrromethanes, e.g. II, and of N-confused dipyrromethanes, e.g. III. [on SciFinder(R)]
Références
- Titre
- An efficient method for the synthesis of unsymmetrical 2,2'-bis(pyrrolyl)alkanes.
- Type de publication
- Article de revue
- Année de publication
- 2010
- Auteurs
- Murat-Onana, Marie Laure, Berini Christophe, Minassian Frédéric, Pelloux-Leon Nadia, and Denis Jean-Noël
- Revue
- Org. Biomol. Chem.
- Volume
- 8
- Pagination
- 2204–2211
- ISSN
- 1477-0520
- DOI
- 10.1039/c001800g
Soumis le 12 avril 2018