Département de chimie moléculaire

A new strategy for the prepn. of unsym. 2,2'-bis(pyrrolyl)alkanes has been developed. It involved the condensation of pyrrole derivs. onto N-benzylhydroxylamines in the presence of HCl. This two-step procedure provided access to a wide variety of 2,2'-dipyrromethanes, e.g. I. It has also been extended to the synthesis of tripyrromethanes, e.g. II, and of N-confused dipyrromethanes, e.g. III. [on SciFinder(R)]