An efficient method for the synthesis of unsymmetrical 2,2'-bis(pyrrolyl)alkanes.

A new strategy for the prepn. of unsym. 2,2'-bis(pyrrolyl)alkanes has been developed. It involved the condensation of pyrrole derivs. onto N-benzylhydroxylamines in the presence of HCl. This two-step procedure provided access to a wide variety of 2,2'-dipyrromethanes, e.g. I. It has also been extended to the synthesis of tripyrromethanes, e.g. II, and of N-confused dipyrromethanes, e.g. III. [on SciFinder(R)]

Références

Titre
An efficient method for the synthesis of unsymmetrical 2,2'-bis(pyrrolyl)alkanes.
Type de publication
Article de revue
Année de publication
2010
Revue
Org. Biomol. Chem.
Volume
8
Pagination
2204–2211
ISSN
1477-0520
Soumis le 12 avril 2018