Efficient Buchwald-Hartwig-Migita Cross-Coupling for DNA Thio-glycoconjugation.
An efficient method for the thio-glycoconjugation of iodinated oligonucleotides by Buchwald-Hartwig-Migita cross-coupling under mild conditions is reported. The method enables divergent synthesis of many different functionalized thioglycosylated ODNs in good yields, without affecting the integrity of the other A, C, and G nucleobases. [on SciFinder(R)]
Références
- Titre
- Efficient Buchwald-Hartwig-Migita Cross-Coupling for DNA Thio-glycoconjugation.
- Type de publication
- Article de revue
- Année de publication
- 2018
- Auteurs
- Probst, Nicolas, Lartia Remy, Thery Oceane, Alami Mouad, Defrancq Eric, and Messaoudi Samir.
- Revue
- Chem. - A Eur. J.
- Volume
- 24
- Pagination
- 1795–1800
- ISSN
- 0947-6539
Soumis le 5 avril 2019