Didecarboxylative Iron-Catalyzed Bidirectional Aldolization towards Diversity-Oriented Ketodiol Synthesis

1,3-Acetonedicarboxylic acid was selectively activated by Fe(acac)3, providing a synthetic platform for rapid synthesis of keto-3,3′-diols. The bidirectional aldol reaction was efficient for challenging aliphatic aldehydes, providing a rapid route to potentially bioactive complex structures.

Références

Titre
Didecarboxylative Iron-Catalyzed Bidirectional Aldolization towards Diversity-Oriented Ketodiol Synthesis
Type de publication
Article de revue
Année de publication
2015
Revue
Chemistry – A European Journal
Volume
21
Ticket
42
Pagination
14717–14722
Soumis le 7 septembre 2022