Didecarboxylative Iron-Catalyzed Bidirectional Aldolization towards Diversity-Oriented Ketodiol Synthesis
1,3-Acetonedicarboxylic acid was selectively activated by Fe(acac)3, providing a synthetic platform for rapid synthesis of keto-3,3′-diols. The bidirectional aldol reaction was efficient for challenging aliphatic aldehydes, providing a rapid route to potentially bioactive complex structures.
Références
- Titre
- Didecarboxylative Iron-Catalyzed Bidirectional Aldolization towards Diversity-Oriented Ketodiol Synthesis
- Type de publication
- Article de revue
- Année de publication
- 2015
- Auteurs
- Quintard, Adrien, and Rodriguez Jean
- Revue
- Chemistry – A European Journal
- Volume
- 21
- Ticket
- 42
- Pagination
- 14717–14722
Soumis le 7 septembre 2022