Construction of anti-parallel G-quadruplexes through sequential templated click.

Biol. relevant DNA sequences were assembled onto addressable cyclopeptide scaffolds through sequential oxime and CuAAc reactions. The resulting conjugates are able to fold into well-defined anti-parallel DNA G-quadruplex structures, which exhibit high stability and reduced polymorphism. [on SciFinder(R)]

Références

Titre
Construction of anti-parallel G-quadruplexes through sequential templated click.
Type de publication
Article de revue
Année de publication
2015
Revue
Chem. Commun. (Cambridge, United Kingdom)
Volume
51
Pagination
4850–4853
ISSN
1359-7345
Soumis le 12 avril 2018