Département de chimie moléculaire

A review. Important questions remain unanswered concerning the catalytic mechanism of catechol oxidase, an enzyme with a coupled dinuclear Cu active site, which catalyzes the oxidn. of o-diphenols to o-quinones in presence of O2. Here, the authors try to demonstrate how well-suited biomimetic models could help elucidate the mechanistic pathway involved in the catalytic cycle of the enzyme. Moreover, the use of 19F NMR as a powerful anal. technique is described. [on SciFinder(R)]