Catalytic Intramolecular C(sp3)–H Amination of Carbamimidates
The Rh(II)-catalyzed intramolecular C(sp3)–H amination of carbamimidates allowed new nitrogen heterocycles to be isolated in yields up to 99 %. The reaction was best performed in the presence of the Rh2(esp)2 (esp = alpha,alpha′,alpha′-tetramethyl-1,3-benzenedipropionic acid) complex by using 2,2,2-trichloroethoxysulfonyl-protected compounds. The reaction could be applied to substrates possessing a benzylic, an allylic, a propargylic, or a tertiary C(sp3)–H bond.
Références
- Titre
- Catalytic Intramolecular C(sp3)–H Amination of Carbamimidates
- Type de publication
- Article de revue
- Année de publication
- 2017
- Auteurs
- Grelier, Gwendal, Rey-Rodriguez Romain, Darses Benjamin, Retailleau Pascal, and Dauban Philippe
- Revue
- European Journal of Organic Chemistry
- Volume
- 2017
- Pagination
- 1880–1883
Soumis le 27 septembre 2018