Département de chimie moléculaire

Herein, we describe a hitherto unprecedented trifluoromethylthiolation of N-acyliminiums promoted by boron trifluoride etherate to enable a convenient access to various alpha-amino trifluoromethylthiolate derivatives in good yields. The reaction proceeds under mild conditions, relying on copper(I) trifluoromethylthiolate as a nucleophilic partner.