Bis-ortho-metalation/silylation of unprotected o-phthalic acids. Straightforward access to new silylated N-hydroxyphthalimide (NHPI) analogs.

The one pot, in situ ortho-metalation/silylation of unprotected o-phthalic acids using lithium tetramethylpiperidide (LiTMP) and chlorotrimethylsilane is described. This method gives a straightforward access to silylated phthalic anhydrides. These can be easily converted into the corresponding silylated N-hydroxyphthalimide (NHPI) analogs, which are promising new aerobic oxidn. catalysts.

Références

Titre
Bis-ortho-metalation/silylation of unprotected o-phthalic acids. Straightforward access to new silylated N-hydroxyphthalimide (NHPI) analogs.
Type de publication
Article de revue
Année de publication
2012
Revue
Tetrahedron Lett.
Volume
53
Pagination
48–50
ISSN
0040-4039
Soumis le 12 avril 2018