Asymmetric Synthesis of Functionalized, Monocyclic Chlorocyclobutenes.

The selective synthesis of a variety of stereopure monocyclic chlorocyclobutenes, e.g. I, is described. These derivs. could be coupled with Grignard reagents; two dienes from coupling with vinylmagnesium bromide reacted smoothly with maleic anhydride to yield illudol-related [4 + 2] cycloadducts, e.g. II. [on SciFinder(R)]

Références

Titre
Asymmetric Synthesis of Functionalized, Monocyclic Chlorocyclobutenes.
Type de publication
Article de revue
Année de publication
2010
Revue
Org. Lett.
Volume
12
Pagination
3994–3997
ISSN
1523-7060
Soumis le 12 avril 2018