Asymmetric Catalytic Synthesis of the Proposed Structure of Trocheliophorolide B
A concise catalytic asymmetric synthesis of the proposed structure of trocheliophorolide B is reported. The synthetic sequence notably features an asymmetric acetaldehyde alkynylation, a Ru-catalyzed alder–ene reaction, and a Zn-ProPhenol ynone aldol condensation. Comparison with the reported data suggests a misassignment of the natural product structure.
Références
- Titre
- Asymmetric Catalytic Synthesis of the Proposed Structure of Trocheliophorolide B
- Type de publication
- Article de revue
- Année de publication
- 2012
- Auteurs
- Trost, Barry. M., and Quintard Adrien
- Revue
- Organic Letters
- Volume
- 14
- Ticket
- 17
- Pagination
- 4698–4700
- ISSN
- 1523-7060
Soumis le 7 septembre 2022