Asymmetric Catalytic Synthesis of the Proposed Structure of Trocheliophorolide B

A concise catalytic asymmetric synthesis of the proposed structure of trocheliophorolide B is reported. The synthetic sequence notably features an asymmetric acetaldehyde alkynylation, a Ru-catalyzed alder–ene reaction, and a Zn-ProPhenol ynone aldol condensation. Comparison with the reported data suggests a misassignment of the natural product structure.

Références

Titre
Asymmetric Catalytic Synthesis of the Proposed Structure of Trocheliophorolide B
Type de publication
Article de revue
Année de publication
2012
Revue
Organic Letters
Volume
14
Ticket
17
Pagination
4698–4700
ISSN
1523-7060
Soumis le 7 septembre 2022