Asymmetric Catalytic Alkynylation of Acetaldehyde: Application to the Synthesis of (+)-Tetrahydropyrenophorol
In control: By controlling the kinetics of alkynylation over aldolization, the challenging asymmetric catalytic alkynylation of acetaldehyde has been realized. The resulting products are attractive synthons which are produced with good to excellent enantiocontrol, and show broad tolerance and applicability, as demonstrated by the synthesis (+)-tetrahydropyrenophorol.
Références
- Titre
- Asymmetric Catalytic Alkynylation of Acetaldehyde: Application to the Synthesis of (+)-Tetrahydropyrenophorol
- Type de publication
- Article de revue
- Année de publication
- 2012
- Auteurs
- Trost, Barry M., and Quintard Adrien
- Revue
- Angewandte Chemie International Edition
- Volume
- 51
- Ticket
- 27
- Pagination
- 6704–6708
Soumis le 7 septembre 2022