Asymmetric addition of aryloxy ethynyl lithium derivatives to N-sulfinyl imines.
Aryloxy ethynyl lithium species can be generated in di-Et ether and efficiently added to aliph. and arom. N-sulfinyl imines in THF, affording aryloxypropargyl sulfinamides in good yield, and in most cases high diastereoselectivity. The diastereoselectivity can be reversed by precomplexation of the N-sulfinyl imine with BF3·OEt2.
Références
- Titre
- Asymmetric addition of aryloxy ethynyl lithium derivatives to N-sulfinyl imines.
- Type de publication
- Article de revue
- Année de publication
- 2013
- Auteurs
- Verrier, Charlie, Carret Sébastien, and Poisson Jean-François
- Revue
- Monatsh. Chem.
- Volume
- 144
- Pagination
- 455–460
- ISSN
- 0026-9247
Soumis le 12 avril 2018