Approach to pactamycin analogues using rhodium(II)-catalyzed alkene aziridination and C(sp3)–H amination reactions
Dirhodium(II)-catalyzed nitrene transfers have been used to prepare a novel synthetic platform bearing the triamino moiety present in pactamycin, jogyamycin and cranomycin. Catalytic intramolecular C(sp3)–H amination and alkene aziridination reactions, the latter followed by a nucleophilic aziridine ring opening, are the key steps of this strategy.
Références
- Titre
- Approach to pactamycin analogues using rhodium(II)-catalyzed alkene aziridination and C(sp3)–H amination reactions
- Type de publication
- Article de revue
- Année de publication
- 2018
- Auteurs
- Rodrigues, Romain, Lazib Yanis, Maury Julien, Neuville Luc, Leboeuf David, Dauban Philippe, and Darses Benjamin
- Revue
- Organic Chemistry Frontiers
- Volume
- 5
- Pagination
- 948–953
Soumis le 2 octobre 2018