Approach to the hyacinthacines: first non-chiral pool synthesis of (+)-hyacinthacine A1.
The first non-chiral pool total synthesis of (+)-hyacinthacine A1 (I) is described. This synthesis is based on an effective [2+2] cycloaddn. of dichloroketene to a Stericol-based enol ether, a diastereoselective dihydroxylation, and an efficient Tamao-Fleming oxidn. [on SciFinder(R)]
Références
- Titre
- Approach to the hyacinthacines: first non-chiral pool synthesis of (+)-hyacinthacine A1.
- Type de publication
- Article de revue
- Année de publication
- 2008
- Auteurs
- P Reddy, Venkatram, Veyron Amael, Koos Peter, Bayle Alexandre, Greene Andrew E., and Delair Philippe.
- Revue
- Org. Biomol. Chem.
- Volume
- 6
- Pagination
- 1170–1172
- ISSN
- 1477-0520
- DOI
- 10.1039/b800445e
Soumis le 12 avril 2018