Approach to the hyacinthacines: first non-chiral pool synthesis of (+)-hyacinthacine A1.

The first non-chiral pool total synthesis of (+)-hyacinthacine A1 (I) is described. This synthesis is based on an effective [2+2] cycloaddn. of dichloroketene to a Stericol-based enol ether, a diastereoselective dihydroxylation, and an efficient Tamao-Fleming oxidn. [on SciFinder(R)]

Références

Titre
Approach to the hyacinthacines: first non-chiral pool synthesis of (+)-hyacinthacine A1.
Type de publication
Article de revue
Année de publication
2008
Revue
Org. Biomol. Chem.
Volume
6
Pagination
1170–1172
ISSN
1477-0520
Soumis le 12 avril 2018