Anti-Bredt N-heterocyclic carbene: an efficient ligand for the gold(I)-catalyzed hydroamination of terminal alkynes with parent hydrazine.
An anti-Bredt N-heterocyclic carbene Au(I) chloride complex I was synthesized by taking advantage of the reversible insertion of the free carbene into the NH bond of hexamethyldisilazane. This precatalyst promotes the parent hydrazine hydroamination of terminal alkynes at room temp. E.g., reaction of 1-hexyne with H2NNH2 in the presence of 5 mol{%} carbene gold complex I/K[B(C6H3(CF3)2)4] in benzene to give BuCMe:NNH2 in 83{%} yield. [on SciFinder(R)]
Références
- Titre
- Anti-Bredt N-heterocyclic carbene: an efficient ligand for the gold(I)-catalyzed hydroamination of terminal alkynes with parent hydrazine.
- Type de publication
- Article de revue
- Année de publication
- 2013
- Auteurs
- Lopez-Gomez, Maria J., Martin David, and Bertrand Guy.
- Revue
- Chem. Commun. (Cambridge, United Kingdom)
- Volume
- 49
- Pagination
- 4483–4485
- ISSN
- 1359-7345
Soumis le 21 janvier 2019