Amperometric biosensor based on the electro-copolymerization of a conductive biotinylated-pyrrole and alginate-pyrrole.

A new matrix was designed and produced, which entailed the co-electropolymn. of pyrrole-biotin (Py-B) with pyrrole-alginate (Alg-Py). The aim was to demonstrate that improved performance could be obtained in a classical model system such as monitoring for the presence of glucose. The sensor construction consisted of the conjugation of biotinylated-glucose oxidase (B-GOx) to B-Py through avidin (Av) bridges, followed by copolymn. with Alg-Py. When the aforementioned set-up did not include the pyrrole-modified alginate but unmodified alginate, its performance values were significantly less. During measurement of the concn. of the model glucose analyte via hydrogen peroxide oxidn., the current was obsd. to be conducted faster to the electrode surface, therefore providing a lower response time, and a higher sensitivity value, using a relatively low enzyme load. [on SciFinder(R)]

Références

Titre
Amperometric biosensor based on the electro-copolymerization of a conductive biotinylated-pyrrole and alginate-pyrrole.
Type de publication
Article de revue
Année de publication
2009
Revue
Synth. Met.
Volume
159
Pagination
1117–1122
ISSN
0379-6779
Soumis le 12 avril 2018