Département de chimie moléculaire

Reactivity of Pyrido[4,3,2-kl]acridines: Regioselective Formation of 6-Substituted Derivatives., Bouffier, Laurent, Demeunynck Martine, Milet Anne, and Dumy Pascal , J. Org. Chem., Volume 69, Number 23, p.8144–8147, (2004)

Cyclodecapeptides to mimic the radical site of tyrosyl-containing proteins., Hossain, Mohammed Akhter, Thomas Fabrice, Hamman Sylvain, Saint-Aman Eric, Boturyn Didier, Dumy Pascal, and Pierre Jean-Louis. , J. Pept. Sci., Volume 12, Number 9, p.612–619, (2006)

Redox-Active Biomolecular Architectures and Self-Assembled Monolayers Based on a Cyclodecapeptide Regioselectively Addressable Functional Template., Devillers, Charles H., Boturyn Didier, Bucher Christophe, Dumy Pascal, Labbe Pierre, Moutet Jean-Claude, Royal Guy, and Saint-Aman Eric , Langmuir, Volume 22, Number 19, p.8134–8143, (2006)

Activatable probes for non-invasive small animal fluorescence imaging., Texier, Isabelle, Razkin Jesus, Josserand Veronique, Boturyn Didier, Dumy Pascal, Coll Jean-Luc, and Rizo Philippe. , Nucl. Instruments Methods Phys. Res. Sect. A Accel. Spectrometers, Detect. Assoc. Equip., Volume 571, Number 1+2, p.165–168, (2007)

Aldehydic Oligonucleotide: A Key Intermediate for the Preparation of Oligonucleotide Conjugates Through Oxime Bond Formation., Spinelli, Nicolas, Singh Y, Defrancq Eric, and Dumy Pascal , Nucleosides. Nucleotides Nucleic Acids, Volume 26, Number 8-9, p.883–887, (2007)

Designed amyloid $\beta$ peptide fibril-a tool for high-throughput screening of fibril inhibitors., Dolphin, Gunnar T., Ouberai Myriam, Dumy Pascal, and Garcia Julian. , ChemMedChem, Volume 2, Number 11, p.1613–1623, (2007)

Efficient Surface Patterning of Oligonucleotides Inside a Glass Capillary through Oxime Bond Formation., Dendane, Nabil, Hoang Antoine, Guillard Ludovic, Defrancq Eric, Vinet Francoise, and Dumy Pascal , Bioconjug. Chem., Volume 18, Number 3, p.671–676, (2007)

Fluorescent ADP Sensing in Physiological Conditions Based on Cooperative Inhibition of a Miniature Esterase., Vial, Laurent, and Dumy Pascal , J. Am. Chem. Soc., Volume 129, Number 16, p.4884–4885, (2007)

In vivo noninvasive optical imaging of receptor-mediated RGD internalization using self-quenched Cy5-labeled RAFT-c(-RGDfK-)4., Jin, Zhao-hui, Razkin Jesus, Josserand Veronique, Boturyn Didier, Grichine Alexei, Texier Isabelle, Favrot Marie-Christine, Dumy Pascal, and Coll Jean-Luc. , Mol. Imaging, Volume 6, Number 1, p.43–55, (2007)

New Solid Support for the Synthesis of 3'-Oligonucleotide Conjugates through Glyoxylic Oxime Bond Formation., Spinelli, Nicolas, Edupuganti Om Prakash, Defrancq Eric, and Dumy Pascal , Org. Lett., Volume 9, Number 2, p.219–222, (2007)

Structure-based design of small peptide inhibitors of protein kinase CK2 subunit interaction., Laudet, Beatrice, Barette Caroline, Dulery Vincent, Renaudet Olivier, Dumy Pascal, Metz Alexandra, Prudent Renaud, Deshiere Alexandre, Dideberg Otto, Filhol Odile, et al. , Biochem. J., Volume 408, Number 3, p.363–373, (2007)

1-Ethoxyethylidene, a New Group for the Stepwise SPPS of Aminooxyacetic Acid Containing Peptides., Foillard, Stephanie, Rasmussen Martin Ohsten, Razkin Jesus, Boturyn Didier, and Dumy Pascal , J. Org. Chem., Volume 73, Number 3, p.983–991, (2008)

Chemical and Biological Evaluations of an 111In-Labeled RGD-Peptide Targeting Integrin Alpha(V) Beta(3) in a Preclinical Tumor Model., Ahmadi, Mitra, Sancey Lucie, Briat Arnaud, Riou Laurent, Boturyn Didier, Dumy Pascal, Fagret Daniel, Ghezzi Catherine, and Vuillez Jean-Philippe. , Cancer Biother. Radiopharm., Volume 23, Number 6, p.691–700, (2008)

Concise Synthesis of 2-Amino-4(3H)-quinazolinones from Simple (Hetero)aromatic Amines., Zeghida, Walid, Debray Julien, Chierici Sabine, Dumy Pascal, and Demeunynck Martine , J. Org. Chem., Volume 73, Number 6, p.2473–2475, (2008)

Cyclic peptides bearing a side-chain tail: a tool to model the structure and reactivity of protein zinc sites., Seneque, Olivier, Bourles Emilie, Lebrun Vincent, Bonnet Estelle, Dumy Pascal, and Latour Jean-Marc. , Angew. Chemie, Int. Ed., Volume 47, Number 36, p.6888–6891, (2008)

A cyclodecapeptide ligand to vitamin B12., Dulery, Vincent, Uhlich Nicolas A., Maillard Noelie, Fluxa Viviana S., Garcia Julian, Dumy Pascal, Renaudet Olivier, Reymond Jean-Louis, and Darbre Tamis. , Org. Biomol. Chem., Volume 6, Number 22, p.4134–4141, (2008)

A fully solid-phase synthesis of biotinylated glycoclusters., Renaudet, Olivier, and Dumy Pascal , Open Glycosci., Volume 1, p.1–7, (2008)

High-throughput identification of combinatorial ligands for DNA delivery in cell culture., Svahn, Mathias G., Rabe Kersten S., Barger Geoffrey, El-Andaloussi Samir, Simonson Oscar E., Didier Boturyn, Olivier Renaudet, Dumy Pascal, Branden Lars J., Niemeyer Christof M., et al. , AIP Conf. Proc., Volume 1062, Number DNA-Based Nanodevices, p.73–88, (2008)

A multimeric quinacrine conjugate as a potential inhibitor of Alzheimer's $\beta$-amyloid fibril formation., Dolphin, Gunnar T., Chierici Sabine, Ouberai Myriam, Dumy Pascal, and Garcia Julian. , ChemBioChem, Volume 9, Number 6, p.952–963, (2008)

Nanomolar heparin detection with an artificial enzyme., Vial, Laurent, and Dumy Pascal , ChemBioChem, Volume 9, Number 18, p.2950–2953, (2008)

NMR and Theoretical Calculations: A Unified View of the Cis/Trans Isomerization of 2-Substituted Thiazolidine Containing Peptides., Jamet, Hélène, Jourdan Muriel, and Dumy Pascal , J. Phys. Chem. B, Volume 112, Number 32, p.9975–9981, (2008)

A novel conformationally constrained parallel G quadruplex., Murat, Pierre, Cressend Delphine, Spinelli Nicolas, Van der Heyden Angeline, Labbe Pierre, Dumy Pascal, and Defrancq Eric , ChemBioChem, Volume 9, Number 16, p.2588–2591, (2008)

Oxime-based synthesis of new chromogenic and fluorogenic oligosaccharides., Renaudet, Olivier, and Dumy Pascal , European J. Org. Chem., Number 32, p.5383–5386, (2008)

Promotion of sugar-lectin recognition through the multiple sugar presentation offered by regioselectively addressable functionalized templates (RAFT): a QCM-D and SPR study., Wilczewski, Marie, Van der Heyden Angeline, Renaudet Olivier, Dumy Pascal, Guerente Liliane, and Labbe Pierre , Org. Biomol. Chem., Volume 6, Number 6, p.1114–1122, (2008)

RAFT Nano-constructs: surfing to biological applications., Boturyn, Didier, Defrancq Eric, Dolphin Gunnar T., Garcia Julian, Labbe Pierre, Renaudet Olivier, and Dumy Pascal , J. Pept. Sci., Volume 14, Number 2, p.224–240, (2008)

Randomized Combinatorial Library of Hetero-glyco-clusters (hGC)., Dulery, Vincent, Renaudet Olivier, Wilczewski Marie, Van der Heyden Angeline, Labbe Pierre, and Dumy Pascal , J. Comb. Chem., Volume 10, Number 3, p.368–371, (2008)

Surface patterning of (bio)molecules onto the inner wall of fused-silica capillary tubes., Dendane, Nabil, Hoang Antoine, Renaudet Olivier, Vinet Francoise, Dumy Pascal, and Defrancq Eric , Lab Chip, Volume 8, Number 12, p.2161–2163, (2008)

Synthesis and biological characterization of targeted pro-apoptotic peptide., Foillard, Stephanie, Jin Zhao-hui, Garanger Elisabeth, Boturyn Didier, Favrot Marie-Christine, Coll Jean-Luc, and Dumy Pascal , ChemBioChem, Volume 9, Number 14, p.2326–2332, (2008)

Synthesis of N-acridinyl-N'-alkylguanidines: Dramatic influence of amine to guanidine replacement on the physicochemical properties., Zeghida, Walid, Debray Julien, Michel Carine, Milet Anne, Dumy Pascal, and Demeunynck Martine , Bioorg. Med. Chem. Lett., Volume 18, Number 17, p.4779–4782, (2008)

Antitumor activity of a self-adjuvanting glyco-lipopeptide vaccine bearing B cell, CD4+ and CD8+ T cell epitopes., Bettahi, Ilham, Dasgupta Gargi, Renaudet Olivier, Chentoufi Aziz Alami, Zhang Xiuli, Carpenter Dale, Yoon Susan, Dumy Pascal, and BenMohamed Lbachir. , Cancer Immunol. Immunother., Volume 58, Number 2, p.187–200, (2009)

Artificial enzyme-based biosensors., Vial, Laurent, and Dumy Pascal , New J. Chem., Volume 33, Number 5, p.939–946, (2009)

Biomolecular assembly by iterative oxime ligations., Renaudet, Olivier, Boturyn Didier, and Dumy Pascal , Bioorg. Med. Chem. Lett., Volume 19, Number 14, p.3880–3883, (2009)

Chemical synthesis, DNA incorporation and biological study of a new photo-cleavable 2'-deoxyadenosine mimic., Berthet, Nathalie, Crey-Desbiolles Caroline, Kotera Mitsuharu, and Dumy Pascal , Nucleic Acids Res., Volume 37, Number 16, p.5237–5245, (2009)

Clustering and Internalization of Integrin $\alpha$v$\beta$3 With a Tetrameric RGD-synthetic Peptide., Sancey, Lucie, Garanger Elisabeth, Foillard Stephanie, Schoehn Guy, Hurbin Amandine, Albiges-Rizo Corinne, Boturyn Didier, Souchier Catherine, Grichine Alexei, Dumy Pascal, et al. , Mol. Ther., Volume 17, Number 5, p.837–843, (2009)

Design and synthesis of novel hybrid metal complex-DNA conjugates: Key building blocks for multimetallic linear DNA nanoarrays., Ghosh, Sumana, Pignot-Paintrand Isabelle, Dumy Pascal, and Defrancq Eric , Org. Biomol. Chem., Volume 7, Number 13, p.2729–2737, (2009)

Drug development in oncology assisted by noninvasive optical imaging., Sancey, L, Dufort S, Josserand V, Keramidas M, Righini C, Rome C, Faure A.-C., Foillard S, Roux S, Boturyn Didier, et al. , Int. J. Pharm., Volume 379, Number 2, p.309–316, (2009)

Efficient conjugation of oligonucleotides through aromatic oxime formation., Murat, Pierre, Spinelli Nicolas, Dumy Pascal, and Defrancq Eric , Bioorg. Med. Chem. Lett., Volume 19, Number 23, p.6534–6537, (2009)

Functionalization of the A ring of pyridoacridine as a route toward greater structural diversity. Synthesis of an octacyclic analogue of eilatin., Bouffier, Laurent, Dinica Rodica, Debray Julien, Dumy Pascal, and Demeunynck Martine , Bioorg. Med. Chem. Lett., Volume 19, Number 16, p.4836–4838, (2009)

A Gadolinium-Binding Cyclodecapeptide with a Large High-Field Relaxivity Involving Second-Sphere Water., Bonnet, Celia S., Fries Pascal H., Crouzy Serge, Seneque Olivier, Cisnetti Federico, Boturyn Didier, Dumy Pascal, and Delangle Pascale. , Chem. - A Eur. J., Volume 15, Number 29, p.7083–7093, S7083/1–S7083/8, (2009)

Highly efficient cell adhesion on beads functionalized with clustered peptide ligands., Foillard, Stephanie, Dumy Pascal, and Boturyn Didier , Org. Biomol. Chem., Volume 7, Number 20, p.4159–4162, (2009)

Oligonucleotide duplexes with tethered photoreactive ruthenium(II) complexes: influence of the ligands and their linker on the photoinduced electron transfer and crosslinking processes of the two strands., Deroo, Stephanie, Le Gac Stephane, Ghosh Sumana, Villien Mathilde, Gerbaux Pascal, Defrancq Eric, Moucheron Cecile, Dumy Pascal, and De Mesmaeker Andree. Kirsch- , Eur. J. Inorg. Chem., Number 4, p.524–532, (2009)

One-pot approach to well-defined biomolecular assemblies by orthogonal chemoselective ligations., Galibert, Mathieu, Dumy Pascal, and Boturyn Didier , Angew. Chemie, Int. Ed., Volume 48, Number 14, p.2576–2579, (2009)

Phenolic oxime oligomers inhibit Alzheimer's amyloid fibril formation and disaggregate fibrils in vitro., Dolphin, Gunnar T., Renaudet Olivier, Ouberai Myriam, Dumy Pascal, Garcia Julian, and Reymond Jean-Louis. , ChemBioChem, Volume 10, Number 8, p.1325–1329, (2009)

Synthesis and Biological Evaluation of Clicked Curcumin and Clicked KLVFFA Conjugates as Inhibitors of $\beta$-Amyloid Fibril Formation., Ouberai, Myriam, Dumy Pascal, Chierici Sabine, and Garcia Julian. , Bioconjug. Chem., Volume 20, Number 11, p.2123–2132, (2009)

Synthesis and evaluation of fused bispyrimidinoacridines as novel pentacyclic analogues of quadruplex-binder BRACO-19., Debray, Julien, Zeghida Walid, Jourdan Muriel, Monchaud David, Dheu-Andries Marie-Louise, Dumy Pascal, Teulade-Fichou Marie-Paule, and Demeunynck Martine , Org. Biomol. Chem., Volume 7, Number 24, p.5219–5228, (2009)

Targeted delivery of activatable fluorescent pro-apoptotic peptide into live cells., Foillard, Stephanie, Sancey Lucie, Coll Jean-Luc, Boturyn Didier, and Dumy Pascal , Org. Biomol. Chem., Volume 7, Number 2, p.221–224, (2009)

Application of click-click chemistry to the synthesis of new multivalent RGD conjugates., Galibert, Mathieu, Sancey Lucie, Renaudet Olivier, Coll Jean-Luc, Dumy Pascal, and Boturyn Didier , Org. Biomol. Chem., Volume 8, Number 22, p.5133–5138, (2010)

Cell adhesion through clustered ligand on fluid supported lipid bilayers., Sandrin, Ludivine, Guerente Liliane, Bernstein Amandine, Basit Hajra, Labbe Pierre, Dumy Pascal, and Boturyn Didier , Org. Biomol. Chem., Volume 8, Number 7, p.1531–1534, (2010)

Electrochemically Controlled Adsorption of Fc-Functionalized Polymers on $\beta$-CD-Modified Self-Assembled Monolayers., Dubacheva, Galina V., Van der Heyden Angeline, Dumy Pascal, Kaftan Oznur, Auzely Rachel, Guerente Liliane, and Labbe Pierre , Langmuir, Volume 26, Number 17, p.13976–13986, (2010)

Linear and branched glyco-lipopeptide vaccines follow distinct cross-presentation pathways and generate different magnitudes of antitumor immunity., Renaudet, Olivier, Dasgupta Gargi, Bettahi Ilham, Shi Alda, Nesburn Anthony B., Dumy Pascal, and BenMohamed Lbachir. , PLoS One, Volume 5, Number 6, p.No pp. given, (2010)