Département de chimie moléculaire

Uniform intratumoral distribution of radioactivity produced using two different radioagents, 64Cu-cyclam-RAFT-c(-RGDfK-)4 and 64Cu-ATSM, improves therapeutic efficacy in a small animal tumor model., Jin, Zhao-hui, Tsuji Atsushi B., Degardin Melissa, Sugyo Aya, Yoshii Yukie, Nagatsu Kotaro, Zhang Ming-Rong, Fujibayashi Yasuhisa, Dumy Pascal, Boturyn Didier, et al. , EJNMMI Res., Volume 8, Number 1, p.1–10, (2018)

Radiotheranostic Agent 64Cu-cyclam-RAFT-c(-RGDfK-)4 for Management of Peritoneal Metastasis in Ovarian Cancer, Jin, Zhao-hui, Tsuji Atsushi B., Degardin Melissa, Sugyo Aya, Obara Satoshi, Wakizaka Hidekatsu, Nagatsu Kotaro, Hu Kuan, Zhang Ming-Rong, Dumy Pascal, et al. , Clinical Cancer Research, 09/2020, Volume 26, Issue 23, p.6230-6241, (2020)

Natural-like replication of an unnatural base pair for the expansion of the genetic alphabet and biotechnology applications, Li, L., Degardin Melissa, Lavergne Thomas, Malyshev D. A., Dhami K., Ordoukhanian P., and Romesberg F. E. , Journal of the American Chemical Society, Volume 136, Number 3, p.826-9, (2014)

Multivalency: influence of the residence time and the retraction rate on rupture forces measured by AFM., Bacharouche, Jalal, Degardin Melissa, Jierry Loic, Carteret Cedric, Lavalle Philippe, Hemmerle Joseph, Senger Bernard, Auzely Rachel, Boulmedais Fouzia, Boturyn Didier, et al. , J. Mater. Chem. B Mater. Biol. Med., Volume 3, Number 9, p.1801–1812, (2015)

Impact of multimeric ferrocene-containing cyclodecapeptide scaffold on host-guest interactions at a β-cyclodextrin covered surface., Perez, Enrique Sanchez, Ritu Ritu, Bruyat Pierrick, Cepeda Celine, Degardin Melissa, Dejeu Jérôme, Boturyn Didier, and Coche-Guérente Liliane , ChemPhysChem, 08/2021, Volume 22, p.2231–2239, (2021)

Heparan sulfate co-immobilized with cRGD ligands and BMP2 on biomimetic platforms promotes BMP2-mediated osteogenic differentiation, Sefkow-Werner, Julius, Machillot Paul, Sales Adria, Castro-Ramirez Elaine, Degardin Melissa, Boturyn Didier, Cavalcanti-Adam Elisabetta Ada, Albiges-Rizo Corinne, Picart Catherine, and Migliorini Elisa , Acta Biomaterialia, 07/2020, Volume 114, p.90 - 103, (2020)

From Peptide Aptamers to Inhibitors of FUR, Bacterial Transcriptional Regulator of Iron Homeostasis and Virulence., Mathieu, Sophie, Cisse Cheickna, Vitale Sylvia, Ahmadova Aynur, Degardin Melissa, Perard Julien, Colas Pierre, Miras Roger, Boturyn Didier, Covès Jacques, et al. , ACS Chem. Biol., Volume 11, Number 9, p.2519–2528, (2016)

Expanding the scope of replicable unnatural DNA: stepwise optimization of a predominantly hydrophobic base pair, Lavergne, Thomas, Degardin Melissa, Malyshev D. A., Quach H. T., Dhami K., Ordoukhanian P., and Romesberg F. E. , Journal of the American Chemical Society, Volume 135, Number 14, p.5408-19, (2013)

Development of a selective cell capture and release assay: impact of clustered RGD ligands., Degardin, Melissa, Thakar D, Claron M, Richter Ralf P., Guerente Liliane, and Boturyn Didier , J. Mater. Chem. B Mater. Biol. Med., Volume 5, Number 24, p.4745–4753, (2017)

$\alpha$V$\beta$3 Integrin-Targeted Radionuclide Therapy with 64Cu-cyclam-RAFT-c(-RGDfK-)4., Jin, Zhao-hui, Furukawa Takako, Degardin Melissa, Sugyo Aya, Tsuji Atsushi B., Yamasaki Tomoteru, Kawamura Kazunori, Fujibayashi Yasuhisa, Zhang Ming-Rong, Boturyn Didier, et al. , Mol. Cancer Ther., Volume 15, Number 9, p.2076–2085, (2016)

67Cu-Radiolabeling of a multimeric RGD peptide for αVβ3 integrin-targeted radionuclide therapy: stability, therapeutic efficacy, and safety studies in mice., Jin, Zhao-hui, Furukawa Takako, Ohya Tomoyuki, Degardin Melissa, Sugyo Aya, Tsuji Atsushi B., Fujibayashi Yasuhisa, Zhang Ming-Rong, Higashi Tatsuya, Boturyn Didier, et al. , Nucl. Med. Commun., Volume 38, Number 4, p.347–355, (2017)